Religion and Ethics Forum

General Category => Science and Technology => Topic started by: Free Willy on January 25, 2018, 11:46:01 AM

Title: First cloned primate
Post by: Free Willy on January 25, 2018, 11:46:01 AM
Monkey see, Monkey two.
Title: Re: First cloned primate
Post by: Humph Warden Bennett on January 25, 2018, 11:49:21 AM
A link would help  :)
Title: Re: First cloned primate
Post by: Nearly Sane on January 25, 2018, 11:54:14 AM
A link would help  :)


http://www.bbc.co.uk/news/health-42809445
Title: Re: First cloned primate
Post by: floo on January 25, 2018, 12:18:03 PM
Human cloning, which is likely one day, is worrying. Even if it is intended for the best of reasons, in the wrong hands it would be catastrophic. Hitler, for instance, would probably have been thrilled to have clones of himself and like minded psychos. :o
Title: Re: First cloned primate
Post by: Nearly Sane on January 25, 2018, 12:24:05 PM
Human cloning, which is likely one day, is worrying. Even if it is intended for the best of reasons, in the wrong hands it would be catastrophic. Hitler, for instance, would probably have been thrilled to have clones of himself and like minded psychos. :o


Put The Boys From Brazil down

Title: Re: First cloned primate
Post by: Sassy on January 25, 2018, 12:32:47 PM
It is frightening to think of someone cloned. But cloning the flesh would not bring the Spirit/Soul back.
The most frightening aspect is that they would lose the humane side of their nature and be born void of conscience and proper human feeling.
Worrying? Maybe?
Title: Re: First cloned primate
Post by: Free Willy on January 25, 2018, 12:45:08 PM
Identical twins are natural clones.
I believe artificial clones need a jolt of electricity to get the first cell going. Just like Frankenstein.
Title: Re: First cloned primate
Post by: floo on January 25, 2018, 01:42:32 PM

Put The Boys From Brazil down

Ehhhhhhh?
Title: Re: First cloned primate
Post by: Humph Warden Bennett on January 25, 2018, 01:59:28 PM

http://www.bbc.co.uk/news/health-42809445

Thanks  :)
Title: Re: First cloned primate
Post by: Humph Warden Bennett on January 25, 2018, 02:02:16 PM
Ehhhhhhh?

It is a film

https://en.wikipedia.org/wiki/The_Boys_from_Brazil_(film)
Title: Re: First cloned primate
Post by: floo on January 25, 2018, 03:40:58 PM
It is a film

https://en.wikipedia.org/wiki/The_Boys_from_Brazil_(film)

Right!
Title: Re: First cloned primate
Post by: Nearly Sane on January 25, 2018, 03:49:16 PM
It is a film

https://en.wikipedia.org/wiki/The_Boys_from_Brazil_(film)
And a book - one of the forgotten writers, Ira Levin


https://en.m.wikipedia.org/wiki/The_Boys_from_Brazil_(novel)
Title: Re: First cloned primate
Post by: Walter on January 25, 2018, 03:54:41 PM
It is frightening to think of someone cloned. But cloning the flesh would not bring the Spirit/Soul back.
The most frightening aspect is that they would lose the humane side of their nature and be born void of conscience and proper human feeling.
Worrying? Maybe?
id forgotten you were an expert in this field . Thanks for the information
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 08:40:28 AM
Human cloning, which is likely one day, is worrying. Even if it is intended for the best of reasons, in the wrong hands it would be catastrophic. Hitler, for instance, would probably have been thrilled to have clones of himself and like minded psychos. :o
Why would a cloned person necessarily think like the person from which they were cloned.

Likely they would be brought up years later and in a different environment. I think you are over-egging 'nature' and under-egging 'nurture'. Even our natural clones (identical twins) who are normally brought up in the same environment and, of course, at the same time aren't identical in terms of their thoughts, desires etc.

You mention Hitler - he never had the technology to clone, but he recognised a much more powerful force (one recognised by autocrats over the centuries) - that of indoctrination. If you want people to think and act like you, control their upbringing and education. That's going to far more likely to succeed than cloning.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 08:44:41 AM
Identical twins are natural clones.
I believe artificial clones need a jolt of electricity to get the first cell going. Just like Frankenstein.
You do realise that Frankenstein is a work of fiction, don't you.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 09:04:12 AM
You do realise that Frankenstein is a work of fiction, don't you.
If that's so Davey how come I converse with antiitheists with flat heads, bolts in their necks and badly cut suits, daily, on this forum?
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 09:14:38 AM
If that's so Davey how come I converse with antiitheists with flat heads, bolts in their necks and badly cut suits, daily, on this forum?
You don't

And besides - how would you know - do you have a secret web-cam that somehow reveals what we all look like. That really would be creepy - more so than a fictional monster or a cloned primate.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 09:34:33 AM
You don't

And besides - how would you know
Easy.........hastily stitched and bolted together responses coupled with a complete lack of aesthetic sense.
Title: Re: First cloned primate
Post by: Harrowby Hall on January 26, 2018, 10:46:25 AM

Put The Boys From Brazil down

Isn't Never Let Me Go, by our latest Nobel laureate, a more relevant warning?
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 11:09:56 AM
Isn't Never Let Me Go, by our latest Nobel laureate, a more relevant warning?
Yes, although easily batted away. Justification along those lines requires society to accept that clones are somehow not fully human in a manner that a non clone isn't. Or perhaps more specifically that the clone is not considered to be a individual, in themselves, but somehow really part of the 'parent'. A simple glance at natural clones (identical twins) allays that view - we do not consider identical twins to be one person - we consider them to be two distinct individuals, albeit with the same genetic makeup.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 11:25:51 AM
Yes, although easily batted away. Justification along those lines requires society to accept that clones are somehow not fully human in a manner that a non clone isn't. Or perhaps more specifically that the clone is not considered to be a individual, in themselves, but somehow really part of the 'parent'. A simple glance at natural clones (identical twins) allays that view - we do not consider identical twins to be one person - we consider them to be two distinct individuals, albeit with the same genetic makeup.
Agree.
The trouble with cloning though is always going to revolve around a perceived close proximity to eugenics.
For instance, if an Einstein or a David Davis can be produced naturally, there must be a special eugenicky reason for cloning.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 11:33:47 AM
Agree.
The trouble with cloning though is always going to revolve around a perceived close proximity to eugenics.
For instance, if an Einstein or a David Davis can be produced naturally, there must be a special eugenicky reason for cloning.
Indeed - cloning is considered taboo in a manner that most technologies aren't.

But that is fairly lazy thinking - I think we should consider the actual ethical issues of cloning rather than lazily leaning on fears of eugenics, which frankly is already possible and have been attempted (and largely been demonstrated to fail, due to weakening of the gene pool plus also the rather inconvenient matter for eugenicists that nurture is just as important as nature, if not more so).
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 11:51:15 AM
Indeed - cloning is considered taboo in a manner that most technologies aren't.

But that is fairly lazy thinking - I think we should consider the actual ethical issues of cloning rather than lazily leaning on fears of eugenics, which frankly is already possible and have been attempted (and largely been demonstrated to fail, due to weakening of the gene pool plus also the rather inconvenient matter for eugenicists that nurture is just as important as nature, if not more so).
I disagree, natural means of reproduction seem adequate. Artificial means are technically easier at present and only as difficult as cloning if cloning can be pulled off.

Cloning demands a fundamental shift in human thinking that was not true of artificial methods to date. It is a form of Eugenics because given the success of natural and artificial fertility there must be a reason for a genomic blueprint to be exactly or near replicated.

You seem to be reflecting an attitude of ''if it can be done it should be done.'' Any better reasons?
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 12:38:23 PM
I disagree, natural means of reproduction seem adequate. Artificial means are technically easier at present and only as difficult as cloning if cloning can be pulled off.
Artificial means are not technically easier - selective breeding to generate specific traits has been used successfully for hundreds and thousands of years. The current cloning technique has only been around for 20 years and this is the first successful example in a primate - one of the reasons being that the technique is hugely species-dependent for reasons that scientists don't really understand. And all cloning does is replicate the genetic make-up of an existing organism (the donor of the nucleus) - of itself it cannot be used to enhance any traits, so is effectively useless as a eugenic tool.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 01:14:44 PM
Artificial means are not technically easier - selective breeding to generate specific traits has been used successfully for hundreds and thousands of years. The current cloning technique has only been around for 20 years and this is the first successful example in a primate - one of the reasons being that the technique is hugely species-dependent for reasons that scientists don't really understand. And all cloning does is replicate the genetic make-up of an existing organism (the donor of the nucleus) - of itself it cannot be used to enhance any traits, so is effectively useless as a eugenic tool.
Sorry I meant artificial fertility methods are easier than cloning.
The main point is that the fertility question is answered by artificial and natural methods and cloning is therefore something apart.

To say that cloning is useless as a eugenic tool is nonsense since it must be done to replicate and perpetuate a desired organism based on genes and characteristics. The ultimate in Eugenics I would have thought.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 01:43:21 PM
To say that cloning is useless as a eugenic tool is nonsense since it must be done to replicate and perpetuate a desired organism based on genes and characteristics. The ultimate in Eugenics I would have thought.
No - I think you misunderstand what most people consider eugenics to be, which is about improving genetic traits - cloning would only maintain those currently present. So unless you have someone considered genetically perfect, cloning isn't going to be of much value. And even if you did have someone considered genetically perfect it would only produce more of the same, rather than improve.

So this is distinct from the classic eugenic approaches which are to persuade those with currently desirable characteristics (in the view of the eugenicist) to reproduce with the view of producing offspring that include the combination of those desirable characteristics from both parents, hence deemed to be an improvement on either parent. Also to prevent those with less desirable characteristics (in the view of the eugenicist) from reproducing.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 01:56:52 PM
No - I think you misunderstand what most people consider eugenics to be, which is about improving genetic traits - cloning would only maintain those currently present. So unless you have someone considered genetically perfect, cloning isn't going to be of much value. And even if you did have someone considered genetically perfect it would only produce more of the same, rather than improve.

So this is distinct from the classic eugenic approaches which are to persuade those with currently desirable characteristics (in the view of the eugenicist) to reproduce with the view of producing offspring that include the combination of those desirable characteristics from both parents, hence deemed to be an improvement on either parent. Also to prevent those with less desirable characteristics (in the view of the eugenicist) from reproducing.
Yes I follow your understanding. However I think it fair to envisage people will not be cloning people with genetic faults. I move that is within the definition of eugenics.

That aside can you justify or provide a reason why anybody should be cloned apart from the ability to do so?
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 02:14:52 PM
Yes I follow your understanding. However I think it fair to envisage people will not be cloning people with genetic faults. I move that is within the definition of eugenics.
Given that human reproductive cloning has never been demonstrated then we are purely speculating at to the motivations of people. Certainly in the world of animal cloning there have been 2 main motivations - the first creating a consistent livestock, which isn't eugenic (i.e. improving traits) rather than maintenance of desirable traits. The second is much more personal. I believe there have been cases where individuals have looked to clone a much loved pet who has died. There is no suggestion that that pet lacked genetic faults - unlikely, certainly in the world of pedigree pets where many breed are in fact desired due to their inherent genetic faults.

That aside can you justify or provide a reason why anybody should be cloned apart from the ability to do so?
Various types of mitochondrial diseases.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 02:19:28 PM
Given that human reproductive cloning has never been demonstrated then we are purely speculating at to the motivations of people. Certainly in the world of animal cloning there have been 2 main motivations - the first creating a consistent livestock, which isn't eugenic (i.e. improving traits) rather than maintenance of desirable traits. The second is much more personal. I believe there have been cases where individuals have looked to clone a much loved pet who has died. There is no suggestion that that pet lacked genetic faults - unlikely, certainly in the world of pedigree pets where many breed are in fact desired due to their inherent genetic faults.
Various types of mitochondrial diseases.
I think your inclusion of the word consistent is just avoiding the word better, So still Eugenic.
The mitochondrial issue is dealt with by ''three parent'' methods surely.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 02:20:21 PM
That aside can you justify or provide a reason why anybody should be cloned apart from the ability to do so?
And you need to recognise the distinction between 'reproductive cloning' and 'therapeutic cloning' - the latter does not aim at creating a cloned organism, but the generation of early stage stem cells for study and/or ultimate therapeutic use. There are loads of reasons why 'therapeutic cloning' is useful and indeed there are many studies ongoing, including in the UK, using the technique, which is lawful provided a licence is obtained from the HFEA.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 02:23:00 PM
The mitochondrial issue is dealt with by ''three parent'' methods surely.
Not necessarily and there are proposed methods that are, in effect, cloning, while the 3 parent approach wouldn't be. My point is merely to indicate that there may be circumstances where cloning might be justified other than on the basis of 'just to see if we can do it' or some eugenic motive. Whether this is justified ethically or legally is a different matter.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 02:25:57 PM
I think your inclusion of the word consistent is just avoiding the word better, So still Eugenic.
I disagree - the process of selective breeding within a pool of livestock to enhance particular traits (via deemed improvement in the genetic characteristics of individual animals) is clearly eugenic - not that we seem particularly bothered for farm animals. Maintaining those traits within the population (rather than improving on them) does really seem to fit with the notion of eugenics which is all about perceived improvement.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 02:34:39 PM
And you need to recognise the distinction between 'reproductive cloning' and 'therapeutic cloning' - the latter does not aim at creating a cloned organism, but the generation of early stage stem cells for study and/or ultimate therapeutic use. There are loads of reasons why 'therapeutic cloning' is useful and indeed there are many studies ongoing, including in the UK, using the technique, which is lawful provided a licence is obtained from the HFEA.
I do...but what a strange reply! There is a world apart from cloning cells and producing a clone as in the case of the full term live borne organism. What would be the function of the latter?
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 02:49:26 PM
I do...but what a strange reply! There is a world apart from cloning cells and producing a clone as in the case of the full term live borne organism.
So-called therapeutic cloning isn't about 'cloning cells' is is about producing a cloned embryo which is then used to derive cells. But that early stage embryo is none-the-less produced and with different motivation could, theoretically, be implanted to produce a full term live born organism.

I recognise the massive difference due to motivation - not all so, hence the very strong arguments against permitting human somatic cell nuclear transfer (the Dolly the sheep cloning method) for any purposes.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 02:58:23 PM
What would be the function of the latter?
I've already answered that - to allow a woman with certain types of very rare mitochondrial disease to have a baby without the risk of inheriting of that disease. That doesn't appear an unreasonable motivation even if there might be other ways of achieving the same (which come with their own ethical challenges to the conservative ethical community).

Or of course to create a master race - although as I've pointed out that is more science fiction than science fact.

But I think perhaps the wrong question is being asked. Perhaps the more relevant question is a hypothetical one at the moment. Namely, were a cloned human being to be born how would we consider that clone to be in human rights terms. Now my view would be that a cloned human being would be identical in human rights terms to any other human individual. A lot of the issues around cloning (and its taboo) seem to stem from a view that somehow a cloned human being would be different and lesser in human rights terms. But there is no reason why that should be the case, and anyhow it is for society to determine whether this would be so.

I would ask you perhaps to learn a little of the ethical debate that raged in then mid to late 70s surrounding IVF, which included a similar strand of (in my view faulty) thinking. Namely that a 'test tube baby' would somehow be considered not fully human by society, would be considered lesser in human rights terms and therefore harmed by being allowed to exist. That seems a particularly perverse argument now, 40 years on from Louise Brown's birth, but that argument was there none the less.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 03:01:23 PM
So-called therapeutic cloning isn't about 'cloning cells' is is about producing a cloned embryo which is then used to derive cells. But that early stage embryo is none-the-less produced and with different motivation could, theoretically, be implanted to produce a full term live born organism.

I recognise the massive difference due to motivation - not all so, hence the very strong arguments against permitting human somatic cell nuclear transfer (the Dolly the sheep cloning method) for any purposes.
I think you have got the wrong end of the stick. All I am asking here is what would be the purpose of a clone that went the full term and was born? Are you suggesting live complete born organism human clones harvested for organs?
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 03:03:07 PM
I've already answered that - to allow a woman with certain types of very rare mitochondrial disease to have a baby without the risk of inheriting of that disease. That doesn't appear an unreasonable motivation even if there might be other ways of achieving the same (which come with their own ethical challenges to the conservative ethical community).

Or of course to create a master race - although as I've pointed out that is more science fiction than science fact.

But I think perhaps the wrong question is being asked. Perhaps the more relevant question is a hypothetical one at the moment. Namely, were a cloned human being to be born how would we consider that clone to be in human rights terms. Now my view would be that a cloned human being would be identical in human rights terms to any other human individual. A lot of the issues around cloning (and its taboo) seem to stem from a view that somehow a cloned human being would be different and lesser in human rights terms. But there is no reason why that should be the case, and anyhow it is for society to determine whether this would be so.

I would ask you perhaps to learn a little of the ethical debate that raged in then mid to late 70s surrounding IVF, which included a similar strand of (in my view faulty) thinking. Namely that a 'test tube baby' would somehow be considered not fully human by society, would be considered lesser in human rights terms and therefore harmed by being allowed to exist. That seems a particularly perverse argument now, 40 years on from Louise Brown's birth, but that argument was there none the less.
But there are non cloning methods for mitochondrial disease.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 03:09:54 PM
But there are non cloning methods for mitochondrial disease.
There are actually no clearly established techniques yet at all, although there has been a reported success of the so-called 3 parent technique in (as far as I'm aware) a single case. Each couple will be different and there may be circumstances whether the 3 parent technique wont work and another technique - for example somatic cell nuclear transfer may. Is it, in your view, unreasonable to even consider this? Why would this not be a reasonable motivation.

You post seems to imply that the issue of parenthood for sufferers of mitochondrial disease is sorted by other methods - it isn't yet. 
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 03:12:50 PM
Are you suggesting live complete born organism human clones harvested for organs?
Of course not (someone else has already written that book as alluded to upthread). If, as I do, you would consider that a human clone, were they born, would have exactly the same human rights as any other human individual born, then why on earth would you think that organ harvesting would be anything other than the most gross infringement of human rights, and ... murder.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 04:57:06 PM
There are actually no clearly established techniques yet at all, although there has been a reported success of the so-called 3 parent technique in (as far as I'm aware) a single case. Each couple will be different and there may be circumstances whether the 3 parent technique wont work and another technique - for example somatic cell nuclear transfer may. Is it, in your view, unreasonable to even consider this? Why would this not be a reasonable motivation.

You post seems to imply that the issue of parenthood for sufferers of mitochondrial disease is sorted by other methods - it isn't yet.
And your reply seems to imply that cloning is the way forward.
Title: Re: First cloned primate
Post by: ProfessorDavey on January 26, 2018, 08:16:31 PM
And your reply seems to imply that cloning is the way forward.
Nope you are completely missing my point.

You seemed to be implying that no one could ever consider cloning for reproductive purposes, except for sinister reasons and motivation or merely to prove it to be possible. All I am doing is pointing out that were cloning to prove to be effective to allow people suffering from mitochondrial disease (and obviously were it to prove to be more effective than any other technique) then it wouldn't be unreasonable for those people to want to take advantage of that technique and their motives wouldn't be sinister in any way.

Whether it should be allowed, however, is a matter for society to judge on the basis of its ethical acceptability, and likely regulated in law, as is currently the case.
Title: Re: First cloned primate
Post by: Free Willy on January 26, 2018, 08:52:50 PM
Nope you are completely missing my point.

You seemed to be implying that no one could ever consider cloning for reproductive purposes, except for sinister reasons and motivation or merely to prove it to be possible. All I am doing is pointing out that were cloning to prove to be effective to allow people suffering from mitochondrial disease (and obviously were it to prove to be more effective than any other technique) then it wouldn't be unreasonable for those people to want to take advantage of that technique and their motives wouldn't be sinister in any way.

Whether it should be allowed, however, is a matter for society to judge on the basis of its ethical acceptability, and likely regulated in law, as is currently the case.
No I want to here what non eugenic purpose there could be for a clone person. If Eugenics is about improvement then even the case of a cloning to avoid mitochondrial condition could be considered Eugenic outside any question of good or bad.
Title: Re: First cloned primate
Post by: jeremyp on January 27, 2018, 06:56:48 PM
Human cloning, which is likely one day, is worrying.
Human cloning already exists. Identical twins are clones.


Quote
Even if it is intended for the best of reasons, in the wrong hands it would be catastrophic. Hitler, for instance, would probably have been thrilled to have clones of himself and like minded psychos. :o
Do you have any evidence that the trait of being a psychotic dictator is in any way genetic?
Title: Re: First cloned primate
Post by: jeremyp on January 27, 2018, 07:01:27 PM
Isn't Never Let Me Go, by our latest Nobel laureate, a more relevant warning?

I've seen the film. I was never able to suspend my disbelief to the point that the central premise became credible.
Title: Re: First cloned primate
Post by: Steve H on February 16, 2018, 11:37:17 AM
Could be handy if he's got a large diocese to administer.